How adult should Decadent and Depraved be?

Since I've started the project of making a webcomic, I've had to ask myself a lot of questions about what direction to take it in. What should the art be like? Who should the characters be? Will it be funny or serious? But lately, as I learn more about the world (which is reaching that stage in development where it seems to be gaining depth without my control) I have to ask myself another question that has never really occurred to me before: how adult should Decadent and Depraved be?

This really isn't something I've ever had to address with any of my other projects, since all of them were based on family friendly ideas and franchises, but (obviously) a story called Decadent and Depraved is going to go in a bit of a different direction. I already know that the story will contain things like sexual themes, drug use (not even necessarily shown in the Saturday morning cartoon "drugs are bad!" way), and dark ideas such as death and crimes against humanity. While I do want the story to have a strong comedic element and be pretty to look at, I do have to answer myself just who my audience should be. Will the comic have nudity? How explicit should death scenes be? How deep should I go into the elements of drug use and sexuality? So I thought that, since the people most likely to read it (if anyone) are the people who read my journals, I'd ask what they thought I should do. Please give me your opinions, and even if I don't yield to it, I will certainly consider it and tread carefully.